Prismatic Member

A prismatic member is a structural or mechanical component with a constant cross-sectional shape and size along its length, making it a fundamental idealization in engineering analysis. Its behavior is determined by how applied loads produce internal axial force, shear, bending moment, or torque, while the uniform geometry allows engineers to evaluate stress, strain, deformation, and stability using consistent section properties. Prismatic members commonly represent beams, columns, rods, and shafts in structural and mechanical systems. Modeling them supports efficient design, load-carrying assessments, and predictions of failure modes such as excessive deflection, buckling, or yielding.

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Research

JoVE EoE - Prostate Cancer

Individual Lobe Extraction from Prostate: A Technique to Harvest Individual Prostate Lobes from Mouse Prostate

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2023

This video describes a technique to harvest individual lobes from the prostate gland of a mouse model. Individual lobes can then be used for histological analysis and cancer research.

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

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Cited by 13 •

2013

We describe the manufacture of compressed hormone pellets, as well as subcutaneous surgical implantation into mice. This strategy can be combined with the growth of cell and tissue xenografts under the renal capsule of athymic nude mice to evaluate hormonal carcinogenesis and regulation of benign prostate growth.

Extracting Prostate from Mouse Urogenital System: A Technique to Separate Prostate Gland from Other Urinary and Genital System Organs in Male Mouse

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2023

In this video, we describe the procedure for the dissection of the urogenital system or UGS from a male mouse model. This UGS is further dissected ex vivo to isolate the prostate gland and study its role in prostate cancer development.

Intra-prostatic Injection of Cancer Cells: A Technique to Deliver Cancer Cells for Establishing Orthotopic Prostate Cancer Mouse Model

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2023

In this video, we demonstrate the procedure for administering intra-prostatic injection of prostate cancer cells into a mouse model. Orthotopic murine models can be used to study the disease origin and response to treatment therapies in a non-invasive and clinically relevant environment.

Murine Prostate Micro-dissection and Surgical Castration

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Cited by 25 •

2016

This manuscript describes the protocols for prostate micro-dissection and surgical castration in the laboratory mouse. We also depict representative results produced by these protocols. Finally, we discuss the advantages and utilization of these protocols.

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