Als Patients
Als Patients - Related Videos
06:08
Transcranial Pulse Stimulation for Alzheimer's Patients
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2025
This article describes the procedure of transcranial pulse stimulation in patients with Alzheimer's disease. It discusses the indications, methodology, and future prospects in detail.
08:10
Proper Adjustment of Patient Attire during the Physical Exam
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2023
Source: Jaideep S. Talwalkar, MD, and Joseph Donroe, MD, Internal Medicine and Pediatrics, Yale School of Medicine, New Haven, CT In order to optimize the predictive value of the physical examination, the provider must perform maneuvers correctly. The proper use of drapes is an important component of correctly performing physical examination maneuvers. Skin lesions are missed when "inspection" occurs through clothing, crackles are erroneously reported when the lungs are examined through a...
08:29
Establishment and Culture of Patient-Derived Breast Organoids
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Cited by 11 •
2023
A detailed protocol is provided here for establishing human breast organoids from patient-derived breast tumor resections or normal breast tissue. The protocol provides comprehensive step-by-step instructions for culturing, freezing, and thawing human patient-derived breast organoids.
04:00
Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
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Cited by 5 •
2024
Corneal sensitivity testing provides insight into the health of the corneal nerves and helps diagnose ocular surface diseases. We present a concise protocol to qualitatively assess corneal sensitivity that can be readily used by eye care providers across clinical settings.
06:25
High-Throughput In Vitro Assay using Patient-Derived Tumor Organoids
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Cited by 6 •
2021
A highly accurate in vitro high-throughput assay system was developed to evaluate anticancer drugs using patient-derived tumor organoids (PDOs), similar to cancer tissues but are unsuitable for in vitro high-throughput assay systems with 96-well and 384-well plates.
FAQs
Damage involving upper and lower motor neurons can occur alongside changes in emotional expression, executive function, social conduct, or decision-making. This means clinicians should consider behavioral findings together with movement-related symptoms rather than interpreting either domain in isolation. Linking neurological and behavioral observations can support a more complete understanding of an individual’s needs.
Behavioral effects are not uniform because ALS patients may show different combinations of emotional, executive, social, and decision-making changes. Some individuals may have noticeable behavioral symptoms, while others may have few or none. This variability makes individualized evaluation important and prevents clinicians from assuming that a particular behavioral pattern applies to every person with ALS.
Clinicians compare observed behavior with the broader clinical picture, including emotional expression, executive function, social conduct, decision-making, communication, and movement-related difficulties. The goal is not to label every behavioral change as neurological. Recognizing understandable psychological responses to disability alongside possible neurological effects leads to more balanced interpretation and more appropriate support.
Behavioral evaluation examines areas such as emotional expression, executive function, social conduct, and decision-making, while considering the person’s movement and communication difficulties. It helps identify whether observed changes may reflect neurological effects, responses to disability, or both. The resulting information can contribute to communication planning, caregiver support, safety planning, and personalized care.
Information about emotional expression, executive function, social conduct, and decision-making can help care teams adapt communication strategies to the individual. Considering these findings alongside movement and communication difficulties may clarify how a person expresses needs or participates in decisions. This individualized approach can make interactions more responsive and support comprehensive care.
Behavioral changes may affect social conduct, decision-making, emotional expression, or executive function, so caregivers and clinicians may need to plan support around the individual’s specific pattern. Behavioral evaluation provides information that can guide safety planning and caregiver responses. It also helps distinguish support needs from assumptions about motivation or understandable reactions to disability.
Studying behavior adds information beyond movement-related symptoms and can improve understanding of how ALS progresses across individuals. It also helps researchers examine the overlap between motor neuron disease and frontotemporal disorders. Behavioral observations therefore contribute both to individualized clinical assessment and to broader research on neurological changes associated with ALS.