Name: 수학 모델링을 사용 인구 교체 전략의 효과를 예측 (동영상) | JoVE Journal
Uploaded: 2007-07-04T00:00:00.000+00:00
Duration: 20 min 36 s
Description: 학습하세요 수학 모델링을 사용하여 유전자 변형 모기의 인구 교체 전략 효과를 평가하는 방법을. 컴퓨터 시뮬레이션을 통해 생태학적 위험과 윤리적 고려사항을 분석합니다.

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predicting the effectiveness of population replacement strategy using mathematical modeling

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy.  Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies.  The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy. Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies. The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy.  ...

You can't do Experiments on the ecological scale because that isn't an experiment. It's the actual release. What if something goes wrong?Remember these mosquitoes transmit a number of very serious diseases. What if they become super bugs and they start transmitting even more effectively? Maybe they'll start transmitting other diseases that they had not been able to transmit in the past.We really have to formulate our policies based on computer models, just like having computer models for all contingencies in landing someone on the moon. So too, we have to have simulations of all contingencies for what happens after we release gene ape modified mosquitoes. My name's Charles Taylor.I'm a the univers of California Los Angeles in the Department of Ecology and Evolutionary Biology with my students and postdocs. I've been working on mathematical aspects of the attempt to use genetically modified mosquitoes to control malaria. We've taken several different approaches to doing this for different parts of the the problem.And today I'll show you a little bit of our work that we've done the last few years and I'll introduce you to one of my students, John Marshall. The modeling we've been doi

predicting-effectiveness-population-replacement-strategy-using

Research

JoVE Journal

Biology

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Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

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Cryopreserving and Recovering of Human iPS Cells using Complete KnockOut Serum Replacement Feeder-Free Medium

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Using RNA-mediated Interference Feeding Strategy to Screen for Genes Involved in Body Size Regulation in the Nematode C. elegans

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In Vivo Modeling of the Morbid Human Genome using Danio rerio

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Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy

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This article describes the methods for screening the genes controlling plasmodesmal permeability and hence auxin gradient during tropic response. This includes the measurement of the degree of tropic response in hypocotyl of Arabidopsis thaliana and checking plasmodesmal permeability by 8-hydroxypyrene-1,3,6-trisulfonic acid (HPTS) loading and finally callose level assessment.

A Strategy to Validate the Role of Callose-mediated Plasmodesmal Gating in the Tropic Response

학습하세요 수학 모델링을 사용하여 유전자 변형 모기의 인구 교체 전략 효과를 평가하는 방법을. 컴퓨터 시뮬레이션을 통해 생태학적 위험과 윤리적 고려사항을 분석합니다.

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

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