Motor Deficit Analysis

Motor deficit analysis is the systematic assessment of impaired movement and motor behavior, providing a way to quantify changes in physical performance. It works by measuring features such as locomotion, coordination, balance, strength, or task completion and comparing results across individuals, experimental groups, or time points. In behavioral research, these measurements help characterize how neurological injury, disease, genetic changes, or experimental treatments affect motor function. Careful analysis can distinguish subtle deficits from normal variation, support evaluation of disease progression or recovery, and provide objective evidence for studies of brain function and behavior.

Motor Deficit Analysis - Related Videos

Research

JoVE Journal - Medicine

Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

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Cited by 4 •

2017

This study demonstrates the technique to make a minimally invasive and easily reproducible model of spinal cord ischemia in rats. Various degrees of hind limb motor deficit can be produced by controlling the aortic occlusion time.

Research

JoVE Journal - Behavior
Free Sample

Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER): A Low-Cost, Open-Access Automated Gait Analysis System for Assessing Motor Deficits

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Cited by 3 •

2019

We describe a novel gait analysis system, Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER), an open-access automated system for the quantification of gait characteristics in rats that utilizes a novel semitransparent floor to automatically quantify gait. This system was validated using the haloperidol model of Parkinson’s Disease.

Research

JoVE Journal - Medicine
Free Sample

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI

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Cited by 17 •

2011

This video demonstrates modulation of reflex activity, volitional strength and ambulation through clinical and quantitative assessments in individuals with motor incomplete SCI as a result of acute oral administration of a serotonin reuptake inhibitor (SSRI).

Research

JoVE Journal - Behavior

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

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Cited by 2 •

2024

A system for acquiring data from self-initiated individual behavior sessions within a social colony cage setting is presented. The efficacy of this system is demonstrated using an automated skilled reach assessment, enabling the characterization of post-stroke motor impairments, potential behavioral alterations related to motivation, circadian variations, and other innovative dependent variables.

Research

JoVE Journal - Behavior
Free Sample

Detecting Behavioral Deficits in Rats After Traumatic Brain Injury

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Cited by 54 •

2018

The goal of the behavioral tests presented here is to detect functional deficits in rats after traumatic brain injury. Four specific tests are presented that detect deficits in behaviors to reflect the damage to specific brain areas at times extending to one year after injury.

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